The Cancer Degradome: Proteases And Cancer Biology.

The Cancer Degradome: Proteases And Cancer Biology

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ISBN details

  • ISBN 10: 0387690565
  • ISBN 13: 9780387690568


Overview

This book will aim to cover recent knowledge of the composition of the Degradome, how it can be studied using modern approaches such as transcriptomics and mass spectrometry; how gene knockout mice have improved our knowledge of the roles of proteases in cancer; how their activity can be imaged both in vitro and in vivo; the links that have emerged between proteolysis and cell signalling; how the degradome can be a useful source of diagnostic and prognostic markers; and finally new approaches to targeting proteolysis for therapy.



Other Details

  • Publisher: Springer
  • Edition: 2009
  • Dimensions: 6.30 (w) x 9.40 (h) x 1.90 (d)
  • Pages: 926
  • Date Published: 2008
  • Authors: Dylan Edwards, Gunilla Hoyer-Hansen, Francesco Blasi