Tumor-induced Immune Suppression: Mechanisms And Therapeutic Reversal.

Tumor-induced Immune Suppression: Mechanisms And Therapeutic Reversal

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ISBN details

  • ISBN 10: 0387691170
  • ISBN 13: 9780387691176


This monograph, for the first time, presents a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It discusses a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance. There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in a more or less cohesive structure and how they can help to improve immune response to tumors.

Other Details

  • Publisher: Springer
  • Language: Eng English
  • Format: print
  • Edition: 2008
  • Dimensions: ix, 301 p. : ill. ; 25 cm.
  • Pages: 301
  • Date Published: 2007
  • Authors: Dimitry I. Gabrilovich, Dmitry I. Gabrilovich, Hurwitz Andy