This volume comprehensively covers new technologies and methodologies that have appeared for the study of mouse development. First of a 2 part update of volume 225, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993Comprehensively covers: new techniques for the cryopreservation of gametes and embryosproduction of transgenic and null (knockout) animals (use of ES cells)generation of conditional/inducible mutant animalsuse of gene-trap mutagenesisanalysis of allele-specific expressionuse of new reporter constructshumanizing of transgenic animalstranscript profiling of mouse development, imaging of mouse developmentrederivation of animals and use of mouse genomics
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