This authoritatively written text provides a working knowledge of the clinical use of neuromuscular blocking agents in the myriad settings encountered in anesthesia and intensive care medicine. The importance of optimizing efficacy and safety is emphasized throughout. The main focus of this practical text is on the anatomy and physiology of neuromuscular transmission, mechanisms of neuromuscular block and means of neuromuscular assessment. Detailed information is provided on individual effects of depolarizing and nondepolarizing relaxants, including adverse effects and contraindications. Other important topics discussed include relevant neuromuscular disorders and disease states, new problems concerning the usage of succinylcholine, potential pharmacologic interactions and critical issues concerning the use and misuse of relaxants. Each chapter is preceded by an outline and a general discussion of the topic and concludes with self-assessment tests for review.
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