DNA Repair and Replication

DNA Repair and Replication contains an up-to-date review of general principles of DNA replication and an overview of the multiple pathways involved in DNA repair. Specific DNA repair pathways, including base-excision repair, light-dependent direct reversal of UV-damage, nucleotide-excision repair, transcription-coupled repair, double-strand break repair, and mismatch repair, are each discussed in separate chapters. Selected Contents:-Base Excision Repair-Eukaryotic DNA Mismatch Repair-Double Strand Break Repair-Functions of DNA Polymerases-Somatic Hypermutation: A Mutational Panacea