Proteases in Tissue Remodelling of Lung and Heart

Proteases in Tissue Remodelling of Lung and Heart is unique for its comprehensive presentation of protease function in lung and heart under both physiological conditions and major diseases manifesting in these two organs. The individual chapters have been written by leaders in the field who paid much attention to outline in great detail the role of proteases in the pathogenesis, diagnosis and treatment of disease. Available animal models (of disease, transgenic, or knock-out) are extensively referred to and experimental data obtained thereby are discussed in the context of patient-derived data. Newcomers to the field and interested non-specialists will take advantage of the extensive introduction to individual proteases, protease families and the diseases. Understanding is greatly facilitated by the clear and condensed presentation of summarised data in tables and graphs. Thus, the book should be a valuable source for both clinicians and researchers interested in protease function and/or diseases of lung and heart. Proteases in Tissue Remodelling of Lung and Heart: *is devoted to proteases in lung and heart specifically and extensively, *covers major diseases of the lung and heart, *extensively introduces individual proteases (or families thereof), *presents up-to-date patient-derived and experimental data, *covers most aspects of protease function in disease.