Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models and culminating in the development of targeted therapy.
| ISBN-13: | 9783540345923 |
| ISBN-10: | 3540345922 |
| Publisher: | Springer Berlin Heidelberg |
| Publication date: | 2006-12-13 |
| Edition description: | 2007 |
| Pages: | 274 |
| Product dimensions: | Height: 9.25 Inches, Length: 6.25 Inches, Weight: 1.43961857086 Pounds, Width: 0.75 Inches |
| Author: | Pier Paolo Pandolfi, Peter K. Vogt |
| Language: | en |
| Binding: | Hardcover |
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