Advances in Immunology

Key Features* Recent findings related to the roles of proteasomes in the MHC class I-restricted antigen processing pathway* New observations and insights on V(D)J recombination* Structure, function, and mechanisms of regulation of mammalian Ets transcription factors* Processes of B2m assembly and peptide loading and the involving molecules* Current concepts and enigmas of lymphocyte homing* Description of plasmacytomagenesis in mice and insights into the cellular and molecular biology of human plasma cell dyscrasias* Summary of the rationale for anti TNF antibody therapy and its clinical effects