Analysis for Drugs and Metabolites Including Anti-infective Agents (Methodological Surveys in Biochemistry and Analysis Vol 20)

This book focuses on the bioanalysis vital for drug development, and provides a review of the latest advances in the methodology and techniques used in trace-level analysis of drugs in body fluids. Subtle chromatography and detection, with appropriate sample preparation, feature throughout. Analysis for Drugs and Metabolites, Including Anti-infective Agents is divided into three sections policies for method validation and ensuring sound results acceptable to the authorities; the bioanalysis of anti-infective drugs, ranging from ¯-lactams to anti-parasitics and anti-virals, with procedural details and information accounts of method-development rationale and problems; and other drug types, plus recent assay approaches such as SFC and laser-induced fluorescence.