Animal Modelling in Surgical R

An animal model is "a living organism with an inherited, naturally acquired or induced pathological process that in one or more respects closely resembles the same phenomenon in man" (Wesslers, National Institute of Health, 1976).Animal Modelling in SurgicalResearchclearly describes animal models used in gastrointestinal, vascular, endocrine, urologic, central nervous system, and transplantation surgery research and highlights their relevance to the study of human disease. Tumour models are also described, including those of the gastrointestinal tract and breast. The fundamental differences between various animal species and the implications for the choice of animal model are explored in an opening chapter on comparative biology, while a system by system approach ensures complete coverage of the models used in different surgical fields. This invaluable book gives a system-based description of the most appropriate animal models for surgical research, highlights relevance of particular mo