Beta-Lactam Antibiotics for Clinical Use

Presenting authoritative reviews of the sources of beta-lactam antibiotics, their mechanisms of action, manufacture, clinical utility, and pharmacology, this important volume gathers together the work of 33 distinguished experts to provide the most complete coverage of these drugs available in a single source. Beta-Lactam Antibiotics for Clinical Use organizes information from microbiology, fermentation science, organic chemistry, clinical medicine, pharmacokinetics, and pharmacodynamics in a unified, interdisciplinary approach ... focuses on the beta-lactams that are, or will shortly be, clinically significant ... identifies both present and projected markets for each antibiotic ... and examines general manufacturing methods for preparing each antibiotic, including the fermentation of intermediates. Containing over 2,300 bibliographic citations of the literature and numerous tables, drawings, and photographs, this book comprises a unique reference for microbiologists and cell biologists; pharmacologists; R & D personnel and research supervisors in the pharmaceutical industry; chemotherapists; toxicologists; industrial and medicinal chemists and biochemists; graduate students in microbiology and pharmacology; and continuing education and staff training programs in microbiology and pharmacology. Book jacket.