cancer_chemotherapy_and_biotherapy-principles_and_practice

Thoroughly revised and enlarged, this book presents a comprehensive, detailed description of the properties and clinical use of anticancer drugs. It provides the latest information on all aspects of drug mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. Particular emphasis is placed on the rationale for the use of drugs in specific schedules and combinations, and guidelines are provided by dose adjustment in particular situations. This edition includes chapters on Endocrine Therapies, Antifolates, 5-Fluoropyrimidines, Cytidine Analogues, Purine Antimetabolites, Hydroxyurea, Antimicrotubule Agents, Alkylating Agents, Antitumor Antibiotics, Anthracyclines, Topoisomerase II Inhibitors, Enzyme Therapy and Anti-HIV Drugs.