Chemogenomics in Drug Discovery A Medicinal Chemistry Perspective, Volume 22

Chemogenomics brings together the most powerful concepts in modern chemistry and biology, linking combinatorial chemistry with genomics and proteomics. This first reference devoted to the topic covers all stages of the early drug discovery process, from target selection to compound library and lead design. From the Contents: ∗ Masterkeys and Privileged Structures ∗ Drug Discovery from Side Effects ∗ Chemical Genetics in Drug Discovery ∗ Knowledge-based Discovery of Biological Targets ∗ Chemical Kinomics ∗ Compound Library and Template Design ∗ Computational Filters in Lead Generation ∗ Ligand-based Design of Focused Libraries ∗ Natural Product-derived Combinatorial Libraries With the combined expertise of 15 research groups from academia and leading pharmaceutical companies, this reference is indispensable reading for every drug developer and medicinal chemist who wants to stay ahead in the search for new and improved drugs.