Product Description This indispensable book covers all aspects of the large, complex, and evolving field of cardiovascular pharmacology in detail. Topics include the basic biochemical, hemodynamic, and electrophysiological aspects of cardiovascular pharmacology, pharmacokinetics, and drug treatment of the various cardiovascular disorders. From the Back Cover Medicine is an ever-changing science and few areas of medical practice have developed more in the last thirty years than has the drug treatment of cardiovascular disease. It is now possible not only to provide symptomatic relief for most cardiac conditions, but to actively delay the progression of a number of cardiac and vascular disease processes. In parallel with these therapeutic advances has been the growth in our understanding of the cellular action of cardiac drugs, principally through greater knowledge of receptor and molecular pharmacology. This book aims to provide readers with an overview of the principles and practice underlying cardiovascular pharmacology. The first three chapters provide a short introduction to some of the concepts used to describe aspects of the cardiovascular function, summarise the cellular modes of action of the principal cardiovascular drugs, and document the factors which influence the concentration of drugs at their sites of action and the intensity of their effects as a function of time. The remaining chapters focus on the drug treatment of individual diseases. Each chapter outlines the pathophysiology of the condition, the evidence for drug treatment, and the clinical pharmacology of the agents used to treat the diseases. A listing of key references and a glossary of common terms used in cardiovascular pharmacology are also included. On account of the strong clinical background of the author and the plethora of outcome trials in the drug treatment of cardiovascular disease, greater emphasis has been placed on drug therapeutics and the results of clinical trials rather than on basic pharmacology. Written by an experienced clinical pharmacologist and active physician, this book will be useful reading for undergraduates in medicine, postgraduate students preparing for the MRCP examination, pharmacists, cardiologists and physicians involved in general and research training.
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