Helicobacter pylori Molecular and Cellular Biology

An awe-inspiring amount of knowledge has been acquired about Helicobacter pylori biology over the last decade. The diversity of approaches employed by scientists from different fields and the sheer numbers of publications produced make it difficult for even the most diligent reader to stay abreast of progress on this fascinating pathogen. In this book leading international scientists distil exciting findings from this vast body of literature to produce comprehensive and topical reviews on the molecular and cellular biology of H. pylori. The book begins with background chapters covering the history, taxonomy, and epidemiology of H. pylori infection and associated diseases. It continues with chapters on host responses including immunity, apoptosis and animal models followed by chapters on virulence factors and vaccine development. The final section summarizes genome analyses, molecular typing and population genetics. Chapters are independent and can be read in any desired sequence. The book will be extremely useful both to graduate students and to scientists not yet familiar with this area. In addition it will serve as a source of topical summaries of recent developments within this highly active area of research to Helicobacter experts. This book is essential reading for all researchers and clinicians working in the Helicobacter and related fields.