Pharmaceutical Dosage Forms Capsules

Pharmaceutical Dosage Forms: Capsules covers the development, composition, and manufacture of capsules. Despite the important role that capsules play in drug delivery and product development, few comprehensive texts on the science and technology of capsules have been available for the research and academic environments. This text addresses this gap, discussing how capsules provide unique capabilities and options for dosage form design and formulation. Featured Topics: Updates the current status of gelatin and gelatin alternatives in capsule shell production, Addresses capsules as a carrier platform both for oral modified release and technologies for solving difficult drug solubility problems, Discusses modeling in support of Quality-by-Design (QbD) and capsule formulation development and manufacture, Updates the role of capsules in clinical trials based on new technologies such as miniaturization for direct "Powder in a Capsule" filling and capsule engineering, Provides practical formulation, manufacturing, and regulatory considerations in development and scale-up, Updates the latest technologies in capsule shell filling and reviews historic developments in capsule filling, Presents many topics authored by experts in the field Book jacket.