The Failing Heart

This comprehensive reference documents recent progress in further elucidating the pathophysiologic mechanisms underlying heart failure and the latest advances in its medical and surgical management. Leading investigators review and synthesize the latest research on the natural history of congestive heart failure; diastolic dysfunction; left ventricular hypertrophy; atrial fibrillation and depressed left ventricular function; post-MI ventricular remodeling; and the role of the renin-angiotensin system in cardiac hypertrophy and heart failure. Thoroughly discussed are the rationale for and use of vasodilators, ACE inhibitors, and inotropes in the management of heart failure. Also given due consideration are the results achieved to date with transplantation, cardiac assist devices, and implantable defibrillators.