Therapeutic Proteins Pharmacokinetics and Pharmacodynamics

Detailing recent advances in one of the most exciting branches of modern biotechnology, Therapeutic Proteins focuses on a critical stage in the development of proteins for therapeutic use: the evaluation of the pharmacokinetic and pharmacodynamic aspects of protein/peptide drugs. Written by both industrial and academic researchers, the book explores the key components of the protein therapeutic industry, form basic research to drug development to drug applications. Therapeutic Proteins offers a wealth of information previously unavailable outside drug companies, and examines some of the major protein/peptide drugs recently licensed or currently being developed. The book reviews the basic principles involved in evaluating toxicity and efficacy, discusses industry standards for protein drug evaluation, and provides state-of-the-art guidelines for designing and interpreting protein pharmacokinetic and pharmacodynamic studies.